D. Denis

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-<i>t</i>-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

John W. Gillard, A W Ford‐Hutchinson, Chi-Chung Chan et al. · Canadian Journal of Physiology and Pharmacology · 1989 · 328 citations

Medicine, Biochemistry, Pharmacology +14

1-YEAR CONTROLLED RANDOMISED TRIAL OF PREVENTION OF EARLY POSTMENOPAUSAL BONE LOSS BY INTRANASAL CALCITONIN

Jean‐Yves Reginster, Adelin Albert, MP Lecart et al. · The Lancet · 1987 · 202 citations

Medicine, Endocrinology, Bone Metabolism +8

Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(<i>t</i>-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor

Christine Brideau, Christine Chan, S. Charleson et al. · Canadian Journal of Physiology and Pharmacology · 1992 · 113 citations

Medicine, Pharmacology, Biochemical Pharmacology +12

From indomethacin to a selective COX-2 inhibitor: Development of indolalkanoic acids as potent and selective cyclooxygenase-2 inhibitors

W. Cameron Black, Christopher I. Bayly, Michel Belley et al. · Bioorganic & Medicinal Chemistry Letters · 1996 · 108 citations

Medicine, Medicinal Chemistry, Pharmacology +10

Characterization of the activity of purified recombinant human 5-lipoxygenase in the absence and presence of leukocyte factors.

D. Denis, Jean‐Pierre Falgueyret, Denis Riendeau et al. · Journal of Biological Chemistry · 1991 · 77 citations · Full text

Life Sciences, Biochemistry, Immunology +15