John W. Gillard

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

Mathieu J.M. Bertrand, Snezana Milutinovic, Kathleen M. Dickson et al. · Molecular Cell · 2008 · 1.1K citations

Tumor Biology, Cell Regulation, Medicine +8

Requirement of a 5-lipoxygenase-activating protein for leukotriene synthesis

Richard A. F. Dixon, Ronald E. Diehl, Evan E. Opas et al. · Nature · 1990 · 775 citations

Biosynthesis, Oxysterol, Biochemistry +6

Identification and isolation of a membrane protein necessary for leukotriene production

Douglas K. Miller, John W. Gillard, Philip J. Vickers et al. · Nature · 1990 · 462 citations

Proteinlipid Interaction, Biosynthesis, Biochemistry +11

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-<i>t</i>-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

John W. Gillard, A W Ford‐Hutchinson, Chi-Chung Chan et al. · Canadian Journal of Physiology and Pharmacology · 1989 · 328 citations

MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes.

Carol A. Rouzer, A. W. Ford‐Hutchinson, Howard E. Morton et al. · Journal of Biological Chemistry · 1990 · 316 citations · Full text

Lipid Peroxidation, Immunology, Membrane Association +20