Kuljeet Vaid

Absence of behavioral abnormalities and neurodegeneration<i>in vivo</i>despite widespread neuronal huntingtin inclusions

Elizabeth Slow, Rona K. Graham, Alexander P. Osmand et al. · Proceedings of the National Academy of Sciences · 2005 · 275 citations · Full text

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Michael E. Østergaard, Amber L. Southwell, Holly Kordasiewicz et al. · Nucleic Acids Research · 2013 · 158 citations · Full text

In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Amber L. Southwell, Niels H. Skotte, Holly Kordasiewicz et al. · Molecular Therapy · 2014 · 145 citations · Full text

Allele-Specific Suppression of Mutant Huntingtin Using Antisense Oligonucleotides: Providing a Therapeutic Option for All Huntington Disease Patients

Niels H. Skotte, Amber L. Southwell, Michael E. Østergaard et al. · PLoS ONE · 2014 · 112 citations · Full text

Engineering, Genetics, Molecular Biology +17

Cleavage at the 586 Amino Acid Caspase-6 Site in Mutant huntingtin Influences Caspase-6 Activation<i>In Vivo</i>

Rona K. Graham, Yu Deng, J. A. Carroll et al. · Journal of Neuroscience · 2010 · 106 citations · Full text