Michael R. Angelastro

.alpha.-Diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases

Michael R. Angelastro, Shujaath Mehdi, Joseph P. Burkhart et al. · Journal of Medicinal Chemistry · 1990 · 145 citations · Full text

Altmetric Attention Score, Peptide Science, Pharmacotherapy +20

Synthesis of peptidyl fluoromethyl ketones and peptidyl .alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

Norton P. Peet, Joseph P. Burkhart, Michael R. Angelastro et al. · Journal of Medicinal Chemistry · 1990 · 116 citations · Full text

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

Shujaath Mehdi, Michael R. Angelastro, Jeffery S. Wiseman et al. · Biochemical and Biophysical Research Communications · 1988 · 100 citations

Protein Function, Molecular Physiology, Signal Transduction +13

An efficient synthesis of novel .alpha.-diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides

Michael R. Angelastro, Norton P. Peet, Philippe Bey · The Journal of Organic Chemistry · 1989 · 69 citations

Medicinal Chemistry, Novel .Alpha.-diketone, Derivative (Chemistry) +14

Peptide aldehydes as inhibitors of HIV protease

Edoardo Sarubbi, Pierfausto Seneci, Michael R. Angelastro et al. · FEBS Letters · 1993 · 68 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12