Shujaath Mehdi

.alpha.-Diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases

Michael R. Angelastro, Shujaath Mehdi, Joseph P. Burkhart et al. · Journal of Medicinal Chemistry · 1990 · 146 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Synthesis of peptidyl fluoromethyl ketones and peptidyl .alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

Norton P. Peet, Joseph P. Burkhart, Michael R. Angelastro et al. · Journal of Medicinal Chemistry · 1990 · 116 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

Inhibition of the proteolysis of rat erythrocyte membrane proteins by a synthetic inhibitor of calpain

Shujaath Mehdi, Michael R. Angelastro, Jeffery S. Wiseman et al. · Biochemical and Biophysical Research Communications · 1988 · 100 citations

Life Sciences, Biochemistry, Cell Biology +12

4',5'-Unsaturated-5'-fluoro adenosine nucleosides: potent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase

James R. McCarthy, Esa T. Jarvi, Donald P. Matthews et al. · Journal of the American Chemical Society · 1989 · 98 citations

Life Sciences, Medicinal Chemistry, Pharmacology +9

Application of a conformationally restricted Phe-Leu dipeptide mimetic to the design of a combined inhibitor of angiotensin I-converting enzyme and neutral endopeptidase 24.11

Gary A. Flynn, Douglas W. Beight, Shujaath Mehdi et al. · Journal of Medicinal Chemistry · 1993 · 67 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11