Joseph P. Burkhart

.alpha.-Diketone and .alpha.-keto ester derivatives of N-protected amino acids and peptides as novel inhibitors of cysteine and serine proteinases

Michael R. Angelastro, Shujaath Mehdi, Joseph P. Burkhart et al. · Journal of Medicinal Chemistry · 1990 · 146 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Substrate-induced inactivation of aromatase by allenic and acetylenic steroids

Brian W. Metcalf, C. Lee Wright, Joseph P. Burkhart et al. · Journal of the American Chemical Society · 1981 · 141 citations

Life Sciences, Biochemistry, Endocrinology +13

Synthesis of peptidyl fluoromethyl ketones and peptidyl .alpha.-keto esters as inhibitors of porcine pancreatic elastase, human neutrophil elastase, and rat and human neutrophil cathepsin G

Norton P. Peet, Joseph P. Burkhart, Michael R. Angelastro et al. · Journal of Medicinal Chemistry · 1990 · 116 citations · Full text

Life Sciences, Biochemistry, Pharmacology +8

The synthesis of α,α-difluoroaldehydes and ketones via claisen rearrangements

Brian W. Metcalf, Esa T. Jarvi, Joseph P. Burkhart · Tetrahedron Letters · 1985 · 71 citations

Natural Sciences, Chemistry, Organic Chemistry +7

Cleavage of tert-butyldimethylsilyl ethers by tetrafluoroborate salts

Brian W. Metcalf, Joseph P. Burkhart, K. JUND · Tetrahedron Letters · 1980 · 69 citations

Natural Sciences, Chemistry, Organic Chemistry +7