Edoardo Sarubbi

A new cytokine-receptor binding mode revealed by the crystal structure of the IL-1 receptor with an antagonist

Herman Schreuder, Chantal Tardif, Susanne Trump-Kallmeyer et al. · Nature · 1997 · 243 citations

Inflammation, Cytokine, Crystal Structure +10

Basal ppGpp level adjustment shown by new spoT mutants affect steady state growth rates and rrnA ribosomal promoter regulation in Escherichia coli

Edoardo Sarubbi, Kenneth E. Rudd, Michael Cashel · Molecular and General Genetics MGG · 1988 · 168 citations

Transcriptional Regulation, Level Adjustment, New Spot Mutants +13

Characterization of the spoT gene of Escherichia coli

Edoardo Sarubbi, Kenneth E. Rudd, Hua Xiao et al. · Journal of Biological Chemistry · 1989 · 107 citations · Full text

SAR and X-ray. A New Approach Combining Fragment-Based Screening and Rational Drug Design:  Application to the Discovery of Nanomolar Inhibitors of Src SH2

Dominique Lesuisse, Gudrun Lange, Pierre Deprez et al. · Journal of Medicinal Chemistry · 2002 · 90 citations · Full text

Acyl Ureas as Human Liver Glycogen Phosphorylase Inhibitors for the Treatment of Type 2 Diabetes

Thomas Klabunde, K. Ulrich Wendt, Dieter Kadereit et al. · Journal of Medicinal Chemistry · 2005 · 68 citations · Full text

Aldo-keto Reductase, Glycobiology, Chemical Biology +18