Joan M. Gushue

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation <i>in vitro</i> and sensitize tumors to doxorubicin <i>in vivo</i>

Holly K. Koblish, Shuyuan Zhao, Carol F. Franks et al. · Molecular Cancer Therapeutics · 2006 · 164 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Novel 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists with improved cellular activity

Kristi Leonard, Juan Marugán, Pierre Raboisson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 60 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +4

Enantiomerically pure 1,4-benzodiazepine-2,5-diones as Hdm2 antagonists

Juan Marugán, Kristi Leonard, Pierre Raboisson et al. · Bioorganic & Medicinal Chemistry Letters · 2006 · 34 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +7

Non-peptidic αvβ3 antagonists containing indol-1-yl propionic acids

Kristi Leonard, Wenxi Pan, Beth Anaclerio et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +6

Biphenylsulfonyl-thiophene-carboxamidine inhibitors of the complement component C1s

Jeremy Travins, Farah Ali, Hui Huang et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 18 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10