Concepedia

Kristi Leonard

KL

Statistics

Publications

29

Citations

1.2K

H-Index

19

Active since

1996

Affiliations

Janssen (United States)(Current)

Johnson & Johnson (United States)

University at Buffalo, State University of New York

Phenex Pharmaceuticals (Germany)

Springhouse

Kristi Leonard is an author at Janssen (United States) specializing in medicinal chemistry, pharmacology, and drug discovery.

ORCID

Publications per year

1996–2025

29

Publications

29

Discovery of a highly selective chemical inhibitor of matrix metalloproteinase-9 (MMP-9) that allosterically inhibits zymogen activation

Robert H. Scannevin, Richard Alexander, Tara Mezzasalma Haarlander et al. · Journal of Biological Chemistry · 2017 · 175 citations · Full text

, , +12

Benzodiazepinedione inhibitors of the Hdm2:p53 complex suppress human tumor cell proliferation <i>in vitro</i> and sensitize tumors to doxorubicin <i>in vivo</i>

Holly K. Koblish, Shuyuan Zhao, Carol F. Franks et al. · Molecular Cancer Therapeutics · 2006 · 164 citations · Full text

, , +15

Pharmacologic modulation of RORγt translates to efficacy in preclinical and translational models of psoriasis and inflammatory arthritis

Xiaohua Xue, Pejman Soroosh, Aimee De Leon-Tabaldo et al. · Scientific Reports · 2016 · 75 citations · Full text

, , +17

Design, Synthesis, and Biological Evaluation of Novel Potent and Selective α<sub>v</sub>β<sub>3</sub>/α<sub>v</sub>β<sub>5</sub> Integrin Dual Inhibitors with Improved Bioavailability. Selection of the Molecular Core

Juan Marugán, Carl L. Manthey, Beth Anaclerio et al. · Journal of Medicinal Chemistry · 2005 · 68 citations · Full text

, , +16

Synthesis and Evaluation of Chalcogenopyrylium Dyes as Potential Sensitizers for the Photodynamic Therapy of Cancer

Kristi Leonard, Marina I. Nelen, Todd P. Simard et al. · Journal of Medicinal Chemistry · 1999 · 66 citations

, , +13

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