Nicholas Marshall

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

Rationally tuning the reduction potential of a single cupredoxin beyond the natural range

Nicholas Marshall, Dewain K. Garner, Tiffany D. Wilson et al. · Nature · 2009 · 294 citations

Single Cupredoxin, Engineering, Biochemistry +5

Deep Dive into Machine Learning Models for Protein Engineering

Yuting Xu, Deeptak Verma, Robert P. Sheridan et al. · Journal of Chemical Information and Modeling · 2020 · 218 citations

Deep Dive, Engineering, Machine Learning +18

IgG Fc domains that bind C1q but not effector Fcγ receptors delineate the importance of complement-mediated effector functions

Chang‐Han Lee, Gabrielle Romain, Wupeng Yan et al. · Nature Immunology · 2017 · 142 citations · Full text

Molecular Immunology, Complement System, Signal Transduction +14

A kinase-cGAS cascade to synthesize a therapeutic STING activator

John A. McIntosh, Zhijian Liu, Brian M. Andresen et al. · Nature · 2022 · 125 citations

Signal Transduction, Biochemistry, Receptor Tyrosine Kinase +5