Mark A. Huffman

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 631 citations

Engineering, Biotechnology, Pharmaceutical Biotechnology +17

Lithium Alkoxides of Cinchona Alkaloids as Chiral Controllers for Enantioselective Acetylide Addition to Cyclic N-Acyl Ketimines

Mark A. Huffman, Nobuyoshi Yasuda, Ann E. DeCamp et al. · The Journal of Organic Chemistry · 1995 · 258 citations

Pharmacy, Chemistry, Medicinal Chemistry +7

Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19

John A. McIntosh, Tamas Benkovics, Steven M. Silverman et al. · ACS Central Science · 2021 · 192 citations · Full text

Life Sciences, Biotechnology, Medicinal Chemistry +14

Palladium‐Catalyzed Tandem Heck Reaction/CH Functionalization—Preparation of Spiro‐Indane‐Oxindoles

Rebecca T. Ruck, Mark A. Huffman, Mary M. Kim et al. · Angewandte Chemie International Edition · 2008 · 188 citations

Natural Sciences, Chemistry, Medicinal Chemistry +14

Iridium-Catalyzed X−H Insertions of Sulfoxonium Ylides

Ian Mangion, Ikenna K. Nwamba, Michael Shevlin et al. · Organic Letters · 2009 · 178 citations

Natural Sciences, Chemistry, Medicinal Chemistry +11