Mark A. Huffman

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

Lithium Alkoxides of Cinchona Alkaloids as Chiral Controllers for Enantioselective Acetylide Addition to Cyclic N-Acyl Ketimines

Mark A. Huffman, Nobuyoshi Yasuda, Ann E. DeCamp et al. · The Journal of Organic Chemistry · 1995 · 256 citations

Lithium Alkoxides, Cinchona Alkaloids, Altmetric Attention Score +9

Palladium‐Catalyzed Tandem Heck Reaction/CH Functionalization—Preparation of Spiro‐Indane‐Oxindoles

Rebecca T. Ruck, Mark A. Huffman, Mary M. Kim et al. · Angewandte Chemie International Edition · 2008 · 187 citations

Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19

John A. McIntosh, Tamas Benkovics, Steven M. Silverman et al. · ACS Central Science · 2021 · 179 citations · Full text

Bioorganic Chemistry, Engineering, Synthetic Virology +19

A General and Efficient 2-Amination of Pyridines and Quinolines

Jingjun Yin, Bangping Xiang, Mark A. Huffman et al. · The Journal of Organic Chemistry · 2007 · 176 citations

Engineering, One-pot Fashion, Organic Chemistry +10