Deeptak Verma

Design of an in vitro biocatalytic cascade for the manufacture of islatravir

Mark A. Huffman, Anna Fryszkowska, Oscar Alvizo et al. · Science · 2019 · 601 citations

Enzyme-catalyzed Reactions, Biomanufacturing, Biosynthesis +15

Deep Dive into Machine Learning Models for Protein Engineering

Yuting Xu, Deeptak Verma, Robert P. Sheridan et al. · Journal of Chemical Information and Modeling · 2020 · 218 citations

Deep Dive, Engineering, Machine Learning +18

Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19

John A. McIntosh, Tamas Benkovics, Steven M. Silverman et al. · ACS Central Science · 2021 · 179 citations · Full text

Bioorganic Chemistry, Engineering, Synthetic Virology +19

A kinase-cGAS cascade to synthesize a therapeutic STING activator

John A. McIntosh, Zhijian Liu, Brian M. Andresen et al. · Nature · 2022 · 125 citations

Signal Transduction, Biochemistry, Receptor Tyrosine Kinase +5

Using enzymes to tame nitrogen-centred radicals for enantioselective hydroamination

Yuxuan Ye, Jingzhe Cao, Daniel G. Oblinsky et al. · Nature Chemistry · 2022 · 122 citations · Full text

Engineering, Biochemistry, Natural Sciences +6