Roderick L. Beijersbergen

Creation of human tumour cells with defined genetic elements

William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations

Tumor Biology, Human Cell, Tumor Heterogeneity +6

Unresponsiveness of colon cancer to BRAF(V600E) inhibition through feedback activation of EGFR

Anirudh Prahallad, Chong Sun, Sidong Huang et al. · Nature · 2012 · 2K citations · Full text

Gastrointestinal Oncology, Medicine, Feedback Activation +8

hEST2, the Putative Human Telomerase Catalytic Subunit Gene, Is Up-Regulated in Tumor Cells and during Immortalization

Matthew Meyerson, Christopher M. Counter, Elinor Ng Eaton et al. · Cell · 1997 · 1.8K citations · Full text

Chromatin, Cell Regulation, Oncogenic Agent +7

A Functional Genetic Approach Identifies the PI3K Pathway as a Major Determinant of Trastuzumab Resistance in Breast Cancer

Katrien Berns, Hugo M. Horlings, Bryan T. Hennessy et al. · Cancer Cell · 2007 · 1.6K citations · Full text

Systems Biology, Breast Oncology, Functional Genetic Approach +9

A large-scale RNAi screen in human cells identifies new components of the p53 pathway

Katrien Berns, E. Marielle Hijmans, Jasper Mullenders et al. · Nature Cell Biology · 2004 · 1.1K citations · Full text

Large-scale Rnai Screen, Natural Sciences, Molecular Biology +7