Shyam B. Mehta

Gelation of a Monoclonal Antibody at the Silicone Oil–Water Interface and Subsequent Rupture of the Interfacial Gel Results in Aggregation and Particle Formation

Shyam B. Mehta, Rachael A. Lewus, Jared S. Bee et al. · Journal of Pharmaceutical Sciences · 2015 · 107 citations

Pharmacy, Biochemistry, Biomedical Engineering +17

Colloidal Instability Fosters Agglomeration of Subvisible Particles Created by Rupture of Gels of a Monoclonal Antibody Formed at Silicone Oil-Water Interfaces

Shyam B. Mehta, John F. Carpenter, Theodore W. Randolph · Journal of Pharmaceutical Sciences · 2016 · 50 citations

Engineering, Biochemistry, Immunology +17

Partial Unfolding of a Monoclonal Antibody: Role of a Single Domain in Driving Protein Aggregation

Shyam B. Mehta, Jared S. Bee, Theodore W. Randolph et al. · Biochemistry · 2014 · 37 citations

Life Sciences, Biochemistry, Molecular Biology +17

Adsorption of recombinant poxvirus L1-protein to aluminum hydroxide/CpG vaccine adjuvants enhances immune responses and protection of mice from vaccinia virus challenge

Yuhong Xiao, Yuhong Zeng, E. A. Alexander et al. · Vaccine · 2012 · 16 citations

Life Sciences, Immunology, Infectious Diseases +17

Best Practices and Guidelines (2022) for Scale-up and Technology Transfer in Freeze Drying Based on Case Studies. Part 2: Past Practices, Current Best Practices, and Recommendations

Serguei Tchessalov, Evgenyi Shalaev, Bakul Bhatnagar et al. · AAPS PharmSciTech · 2023 · 16 citations · Full text

Pharmacy, Food Science, Food Engineering +12