Najib Naamane

DNA methylation profiling identifies epigenetic dysregulation in pancreatic islets from type 2 diabetic patients

Michael Volkmar, Sarah Dedeurwaerder, Daniel A. Cunha et al. · The EMBO Journal · 2012 · 426 citations · Full text

Chromatin, Pancreatic Islets, Epigenetic Change +11

STAT1 Is a Master Regulator of Pancreatic β-Cell Apoptosis and Islet Inflammation

Fabrice Moore, Najib Naamane, Máikel L. Colli et al. · Journal of Biological Chemistry · 2010 · 177 citations · Full text

Apoptosis, Immune Regulation, Immunology +19

Induction of nuclear factor-κB and its downstream genes by TNF-α and IL-1β has a pro-apoptotic role in pancreatic beta cells

Fernanda Ortis, Pierre Pirot, Najib Naamane et al. · Diabetologia · 2008 · 155 citations · Full text

Inflammation, Cytokine, Immune Cell Development +10

Cytokines Interleukin-1β and Tumor Necrosis Factor-α Regulate Different Transcriptional and Alternative Splicing Networks in Primary β-Cells

Fernanda Ortis, Najib Naamane, Daisy Flamez et al. · Diabetes · 2009 · 150 citations · Full text

Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

Pierre Pirot, Najib Naamane, Frédérick Libert et al. · Diabetologia · 2007 · 128 citations · Full text

Insulin Signaling, Protein Expression, Early Degradation +10