Caroline Rynn - Concepedia

Author

Caroline Rynn

Novartis (Switzerland)ORCID

Also Known As

Caroline Rynn

Publications

690

Citations

H-Index

Concepts

All Affiliations

Novartis (Switzerland)Novartis Institutes for BioMedical Research Roche (Switzerland)

About

Caroline Rynn is an author at Novartis (Switzerland) specializing in medicine, pharmacology, and tumor biology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	3	3	273
2	Health Sciences	1	1	51
3	Natural Sciences	1	1	202
4	Cell Biology	1	1	20
5	Microbiology	1	1	51

Caroline Rynn

Publications

423

Citations

H-Index

Page 1

	Year	Citations
Discovery of a Dihydroisoquinolinone Derivative (NVP-CGM097): A Highly Potent and Selective MDM2 Inhibitor Undergoing Phase 1 Clinical Trials in p53wt Tumors Philipp Holzer, Keiichi Masuya, Pascal Furet, Journal of Medicinal Chemistry Dihydroisoquinolinone DerivativeDrug TargetMolecular BiologyPharmacotherapyTumor Biology	2015	202
A distinct p53 target gene set predicts for response to the selective p53–HDM2 inhibitor NVP-CGM097 Sébastien Jeay, Swann Gaulis, Stéphane Ferretti, eLife	2015	87
In vitro assessment of colistin's antipseudomonal antimicrobial interactions with other antibiotics Alasdair MacGowan, Caroline Rynn, Mandy Wootton, Clinical Microbiology and Infection Antimicrobial SusceptibilityHealth SciencesAntibioticsMedicineAntipseudomonal Antimicrobial Interactions	1999	51
Discovery of Novel Allosteric EGFR L858R Inhibitors for the Treatment of Non-Small-Cell Lung Cancer as a Single Agent or in Combination with Osimertinib U. Obst-Sander, Antônio Ricci, Bernd Kuhn, Journal of Medicinal Chemistry	2022	35
In vitro and in vivo characterization of a novel, highly potent p53-MDM2 inhibitor Andrea Vaupel, Philipp Holzer, Stéphane Ferretti, Bioorganic & Medicinal Chemistry Letters MedicinePharmacologyTumor TargetingAnti-cancer AgentTumor Suppressor	2018	20
Preclinical Characterization of a Next-Generation Brain Permeable, Paradox Breaker BRAF Inhibitor Jürgen Wichmann, Caroline Rynn, Thomas Friess, Clinical Cancer Research	2021	18
Identification of cryptolepine metabolites in rat and human hepatocytes and metabolism and pharmacokinetics of cryptolepine in Sprague Dawley rats Arnold Donkor Forkuo, Charles Ansah, David Pearson, BMC Pharmacology and Toxicology	2017	10

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