Shawn Cabral

Structural Basis for AMPK Activation: Natural and Synthetic Ligands Regulate Kinase Activity from Opposite Poles by Different Molecular Mechanisms

Matthew F. Calabrese, Francis Rajamohan, Melissa S. Harris et al. · Structure · 2014 · 179 citations · Full text

Opposite Poles, Molecular Physiology, Signal Transduction +9

Discovery and Optimization of Imidazopyridine-Based Inhibitors of Diacylglycerol Acyltransferase 2 (DGAT2)

Kentaro Futatsugi, Daniel W. Kung, Suvi T. M. Orr et al. · Journal of Medicinal Chemistry · 2015 · 80 citations

Combinatorial Chemistry, Lipid Analysis, Medicinal Chemistry +14

Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing

Jonathan L. Chen, Peiyuan Zhang, Masahito Abe et al. · Journal of the American Chemical Society · 2020 · 78 citations · Full text

Analogue Synthesis, Molecular Biology, Lead Identification +19

Discovery and characterization of novel inhibitors of the sodium-coupled citrate transporter (NaCT or SLC13A5)

Kim Huard, Janice A. Brown, Jessica Jones et al. · Scientific Reports · 2015 · 68 citations · Full text

Medicinal Chemistry, Biochemistry, Citrate Transport +13

PF-07059013: A Noncovalent Modulator of Hemoglobin for Treatment of Sickle Cell Disease

Ariamala Gopalsamy, Ann Aulabaugh, Amey Barakat et al. · Journal of Medicinal Chemistry · 2020 · 40 citations · Full text