Lijiang Shen

Arterial Injury by Cholesterol Oxidation Products Causes Endothelial Dysfunction and Arterial Wall Cholesterol Accumulation

James X. Rong, Shanthini Rangaswamy, Lijiang Shen et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1998 · 70 citations

Medicine, Pharmacokinetics, Pharmacology +9

Comparing In Vitro and In Vivo Activity of 2′-<i>O</i>-[2-(Methylamino)-2-oxoethyl]- and 2′-<i>O</i>-Methoxyethyl-Modified Antisense Oligonucleotides

Thazha P. Prakash, Andrew M. Kawasaki, Edward V. Wancewicz et al. · Journal of Medicinal Chemistry · 2008 · 62 citations

Pharmacy, Molecular Biology, Pharmacology +15

Mechanistic Understanding for the Greater Sensitivity of Monkeys to Antisense Oligonucleotide–Mediated Complement Activation Compared with Humans

Lijiang Shen, Ashley Frazer‐Abel, Paul R. Reynolds et al. · Journal of Pharmacology and Experimental Therapeutics · 2014 · 43 citations

Medicine, Immunology, Pharmacology +7

Cholesterol Oxidation Products Induce Vascular Foam Cell Lesion Formation in Hypercholesterolemic New Zealand White Rabbits

James X. Rong, Lijiang Shen, Yi Hsin Chang et al. · Arteriosclerosis Thrombosis and Vascular Biology · 1999 · 40 citations

Life Sciences, Pathobiology, Pharmacology +15

Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2ʹ-MOE-Modified Antisense Oligonucleotide

Padmakumar Narayanan, Lijiang Shen, Brian R. Curtis et al. · Toxicological Sciences · 2018 · 39 citations · Full text

Medicine, Pharmacology, Toxicology +9