Padmakumar Narayanan

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

Paymaan Jafar‐Nejad, Berit Powers, Armand Soriano et al. · Nucleic Acids Research · 2020 · 121 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Investigation into the Mechanism(s) That Leads to Platelet Decreases in Cynomolgus Monkeys During Administration of ISIS 104838, a 2ʹ-MOE-Modified Antisense Oligonucleotide

Padmakumar Narayanan, Lijiang Shen, Brian R. Curtis et al. · Toxicological Sciences · 2018 · 39 citations · Full text

Medicine, Pharmacology, Toxicology +9

Assessment of the Effects of 2′-Methoxyethyl Antisense Oligonucleotides on Platelet Count in Cynomolgus Nonhuman Primates

Scott P. Henry, Padmakumar Narayanan, Lijiang Shen et al. · Nucleic Acid Therapeutics · 2017 · 28 citations

Medicine, Pharmacology, Clinical Pharmacology +8

Underlying Immune Disorder May Predispose Some Transthyretin Amyloidosis Subjects to Inotersen-Mediated Thrombocytopenia

Padmakumar Narayanan, Brian R. Curtis, Lijiang Shen et al. · Nucleic Acid Therapeutics · 2020 · 27 citations

Medicine, Hematology, Neurology +11

Sequence-specific 2'-O-methoxyethyl antisense oligonucleotides activate human platelets through glycoprotein VI, triggering formation of platelet-leukocyte aggregates

Martina H. Lundberg Slingsby, Prakrith Vijey, I‐Ting Tsai et al. · Haematologica · 2021 · 14 citations · Full text

Medicine, Hematology, Pharmacology +11