Armand Soriano

Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice

Lindsay A. Becker, Brenda Huang, Gregor Bieri et al. · Nature · 2017 · 562 citations · Full text

Lifespan Extension, Knockout Mouse, Molecular Neuroscience +11

Comprehensive Structure–Activity Relationship of Triantennary<i>N</i>-Acetylgalactosamine Conjugated Antisense Oligonucleotides for Targeted Delivery to Hepatocytes

Thazha P. Prakash, Jinghua Yu, Michael T. Migawa et al. · Journal of Medicinal Chemistry · 2016 · 131 citations

The atlas of RNase H antisense oligonucleotide distribution and activity in the CNS of rodents and non-human primates following central administration

Paymaan Jafar‐Nejad, Berit Powers, Armand Soriano et al. · Nucleic Acids Research · 2020 · 112 citations · Full text

Immunology, Molecular Biology, Neurology +17

Antisense oligonucleotide therapy for KCNT1 encephalopathy

Lisseth Estefania Burbano, Melody Li, Nikola Jancovski et al. · JCI Insight · 2022 · 57 citations · Full text

Kcnt1-associated Dee, Neurobiology Of Disease, Molecular Physiology +13

Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice

Krista J. Spiller, Tahiyana Khan, Myrna A. Dominique et al. · Neurobiology of Disease · 2018 · 49 citations · Full text

Matrix Metalloproteinase 9, Molecular Neuroscience, Motor Neurons +9