Andrew L. Markhard

Prolonged Rapamycin Treatment Inhibits mTORC2 Assembly and Akt/PKB

Dos D. Sarbassov, Siraj M. Ali, Shomit Sengupta et al. · Molecular Cell · 2006 · 2.6K citations · Full text

Molecular Pharmacology, Medicine, Receptor Tyrosine Kinase +4

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

Yasemin Sancak, Liron Bar‐Peled, Roberto Zoncu et al. · Cell · 2010 · 2.4K citations · Full text

Protein Function, Molecular Physiology, Signal Transduction +14

EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex

Yasemin Sancak, Andrew L. Markhard, Toshimori Kitami et al. · Science · 2013 · 649 citations · Full text

Molecular Biology, Mitochondrial Uniporter, Molecular Genetics +20

Architecture of the mitochondrial calcium uniporter

Kirill Oxenoid, Ying Dong, Chan Cao et al. · Nature · 2016 · 289 citations · Full text

Biochemistry, Mitochondrial Function, Natural Sciences +6

Discovery of 1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1<i>H</i>)-one as a Highly Potent, Selective Mammalian Target of Rapamycin (mTOR) Inhibitor for the Treatment of Cancer

Qingsong Liu, Jae Won Chang, Jinhua Wang et al. · Journal of Medicinal Chemistry · 2010 · 251 citations · Full text

Drug Target, Pharmacotherapy, Chemical Biology +20