Henry R. Maun

Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent

Mark Merchant, Xiaolei Ma, Henry R. Maun et al. · Proceedings of the National Academy of Sciences · 2013 · 243 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling

Ivan Bosanac, Henry R. Maun, Suzie J. Scales et al. · Nature Structural & Molecular Biology · 2009 · 143 citations

Life Sciences, Biology, Molecular Biology +14

Hedgehog Pathway Antagonist 5E1 Binds Hedgehog at the Pseudo-active Site

Henry R. Maun, Xiaohui Wen, Andreas Lingel et al. · Journal of Biological Chemistry · 2010 · 141 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +7

Suppressor of Fused Regulates Gli Activity through a Dual Binding Mechanism

Mark Merchant, F.F. Vajdos, Mark Ultsch et al. · Molecular and Cellular Biology · 2004 · 124 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

An Allosteric Anti-tryptase Antibody for the Treatment of Mast Cell-Mediated Severe Asthma

Henry R. Maun, Janet Jackman, David F. Choy et al. · Cell · 2019 · 110 citations · Full text

Life Sciences, Immunology, Pharmacotherapy +14