Jirong Lu

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Ronald B. DeMattos, Jirong Lu, Ying Tang et al. · Neuron · 2012 · 411 citations · Full text

In Vivo Deamidation Characterization of Monoclonal Antibody by LC/MS/MS

Lihua Huang, Jirong Lu, Victor J. Wroblewski et al. · Analytical Chemistry · 2005 · 263 citations

Immunology, Glycobiology, Immunotherapy +18

Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A

Ling Liu, Kristine Kikly, Jirong Lu et al. · Journal of Inflammation Research · 2016 · 204 citations · Full text

Clinical Immunology, Immunology, Immune Regulation +16

Balancing charge in the complementarity-determining regions of humanized mAbs without affecting pI reduces non-specific binding and improves the pharmacokinetics

Amita Datta‐Mannan, Arunkumar Thangaraju, Donmienne Leung et al. · mAbs · 2015 · 143 citations · Full text

Immunology, Immunodominance, Peptide Science +28

LY2875358, a Neutralizing and Internalizing Anti-MET Bivalent Antibody, Inhibits HGF-Dependent and HGF-Independent MET Activation and Tumor Growth

Ling Liu, Wei Zeng, Mark A. Wortinger et al. · Clinical Cancer Research · 2014 · 105 citations