Concepedia

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Ronald B. DeMattos, Jirong Lu, Ying Tang, Margaret M. Racke, Cindy A. DeLong, John A. Tzaferis, Justin T. Hole, Beth M. Forster, Peter McDonnell, Feng Liu,

Neuron · 2012 · 411 citations · 50 references

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References

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Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

Clifford R. Jack, David S. Knopman, William J. Jagust et al. · The Lancet Neurology · 2009 · 4.6K citations · Full text

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Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Dale Schenk, Robin Barbour, Whitney Dunn et al. · Nature · 1999 · 3.1K citations

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Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

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Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Frédérique Bard, Catherine Cannon, Robin Barbour et al. · Nature Medicine · 2000 · 2K citations · Full text

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Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

Ronald B. DeMattos, Kelly R. Bales, David J. Cummins et al. · Proceedings of the National Academy of Sciences · 2001 · 1.3K citations · Full text

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