Justin T. Hole

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang, Tyler K. Ulland, Jason D. Ulrich et al. · The Journal of Experimental Medicine · 2016 · 882 citations · Full text

Medicine, Neurobiology, Neuroscience +17

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Ronald B. DeMattos, Jirong Lu, Ying Tang et al. · Neuron · 2012 · 461 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Hong Wang, Yupeng Li, John Ryder et al. · Molecular Neurodegeneration · 2018 · 91 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Xavier Taylor, Isaiah Clark, Griffin J. Fitzgerald et al. · Molecular Neurodegeneration · 2023 · 85 citations · Full text

Life Sciences, Immunology, Neuroscience +17

[O2–14–05]: PRECLINICAL CHARACTERIZATION OF AN ANTIBODY [LY3303560] TARGETING AGGREGATED TAU

Riazul Alam, David A. Driver, Su Wu et al. · Alzheimer s & Dementia · 2017 · 44 citations

Pharmacy, Pharmacokinetics, Pharmacology +17