Justin T. Hole

TREM2-mediated early microglial response limits diffusion and toxicity of amyloid plaques

Yaming Wang, Tyler K. Ulland, Jason D. Ulrich et al. · The Journal of Experimental Medicine · 2016 · 819 citations · Full text

Amyloid β, Immunology, Immune Regulation +21

A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice

Ronald B. DeMattos, Jirong Lu, Ying Tang et al. · Neuron · 2012 · 411 citations · Full text

Genome-wide RNAseq study of the molecular mechanisms underlying microglia activation in response to pathological tau perturbation in the rTg4510 tau transgenic animal model

Hong Wang, Yupeng Li, John Ryder et al. · Molecular Neurodegeneration · 2018 · 87 citations · Full text

Amyloid-β (Aβ) immunotherapy induced microhemorrhages are associated with activated perivascular macrophages and peripheral monocyte recruitment in Alzheimer’s disease mice

Xavier Taylor, Isaiah Clark, Griffin J. Fitzgerald et al. · Molecular Neurodegeneration · 2023 · 78 citations · Full text

[O2–14–05]: PRECLINICAL CHARACTERIZATION OF AN ANTIBODY [LY3303560] TARGETING AGGREGATED TAU

Riazul Alam, David A. Driver, Su Wu et al. · Alzheimer s & Dementia · 2017 · 42 citations

Immunocytochemical Technique, Laboratory Immunology, Soluble Tau Aggregate +16