In Vivo Deamidation Characterization of Monoclonal Antibody by LC/MS/MS

Lihua Huang, Jirong Lu, Victor J. Wroblewski, +2

Analytical Chemistry

ImmunologyGlycobiologyImmunotherapyProtein PurificationBioanalysis +16

Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A

Ling Liu, Kristine Kikly, Jirong Lu, +9

Journal of Inflammation Research

Clinical ImmunologyImmunologyImmune RegulationImmunologic MechanismImmune System +14

Polysorbates 20 and 80 Degradation by Group XV Lysosomal Phospholipase A 2 Isomer X1 in Monoclonal Antibody Formulations

Troii Hall, Stephanie Sandefur, Christopher C. Frye, +2

Journal of Pharmaceutical Sciences

Monoclonal Antibody FormulationsBiochemistryPolysorbates 20Natural SciencesMedicine +8

Molecular mass and carbohydrate structure of prostate specific antigen: Studies for establishment of an international PSA standard

A. Bélanger, Herman van Halbeek, Howard C.B. Graves, +5

The Prostate

Impact of variable domain glycosylation on antibody clearance: An LC/MS characterization

Lihua Huang, Susan Biolsi, Kelly R. Bales, +1

Analytical Biochemistry

Protein GlycosylationVariable Domain GlycosylationBiochemistryAntibody ClearanceLc/ms Characterization +10

A Novel Sample Preparation for Shotgun Proteomics Characterization of HCPs in Antibodies

Lihua Huang, Ning Wang, Charles E. Mitchell, +3

Analytical Chemistry

Genome-wide analysis of DNA G-quadruplex motifs across 37 species provides insights into G4 evolution

Feng Wu, Kangkang Niu, Yong Cui, +12

Communications Biology

Characterization of Poly(ethylene glycol) and PEGylated Products by LC/MS with Postcolumn Addition of Amines

Lihua Huang, P. Clayton Gough, Michael R. DeFelippis

Analytical Chemistry

Ethylene GlycolPostcolumn AdditionEngineeringMacromolecular ChemistryPeptide Engineering +20

Activin Signaling: Effects on Body Composition and Mitochondrial Energy Metabolism

Liunan Li, Joseph Shen, Juan C. Bournat, +6

Endocrinology

Metabolic RateMetabolic DisorderInsulin SignalingOxidative StressObesity +16

Solution Stability of Poloxamer 188 Under Stress Conditions

Tingting Wang, Aaron P. Markham, Steven J. Thomas, +3

Journal of Pharmaceutical Sciences

Materials ScienceEngineeringPolymer StabilitySolution StabilityChemistry +1