Neutrophils as early immunologic effectors in hemorrhage- or endotoxemia-induced acute lung injury

Edward Abraham, Aaron Carmody, Robert Shenkar, +1

American Journal of Physiology-Lung Cellular and Molecular Physiology

Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity

Rebecca Stockton, Robert Shenkar, Issam A. Awad, +1

The Journal of Experimental Medicine

Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling

Zinan Zhou, Alan T. Tang, Weng-Yew Wong, +13

Nature

Developmental BiologyEpendymaVascular MalformationCerebral Cavernous MalformationsVascular Biology +4

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Alan T. Tang, Jaesung P. Choi, Jonathan J. Kotzin, +27

Nature

MedicinePathogenesisVascular MalformationPathologyVascular Biology +7

Nuclear factor-kappa B is activated in alveolar macrophages from patients with acute respiratory distress syndrome

Michael Schwartz, Ernest E. Moore, Frederick A. Moore, +4

Critical Care Medicine

Methylation-induced blocks to in vitro DNA replication

Karen Larson, J Sahm, Robert Shenkar, +1

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

ChromatinNatural SciencesGeneticsDna MethylationMethylation-induced Blocks +6

Involvement of Phosphoinositide 3-Kinases in Neutrophil Activation and the Development of Acute Lung Injury

Ho-Kee Yum, John J. Arcaroli, John Kupfner, +6

The Journal of Immunology

Hemorrhage increases cytokine expression in lung mononuclear cells in mice: involvement of catecholamines in nuclear factor-kappaB regulation and cytokine expression.

Yves Le Tulzo, Robert Shenkar, Debra Kaneko, +4

Journal of Clinical Investigation

Acute Lung InjuryInflammatory Lung DiseaseLung InflammationImmunologyBlood Loss +21

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Aileen A. Ren, Daniel Snellings, YouRong Sophie Su, +25

Nature

Ccm Mutations FuelRadiation OncologyMedicineCell BiologyCancer Research +1

Pathobiology of Human Cerebrovascular Malformations: Basic Mechanisms and Clinical Relevance

Judith Gault, Hemant Sarin, Nabil A. Awadallah, +2

Neurosurgery

ThrombosisIdentical Sporadic CcmVascular DiseaseMedicineCerebrospinal Fluid +13