Jaesung P. Choi

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Alan T. Tang, Jaesung P. Choi, Jonathan J. Kotzin et al. · Nature · 2017 · 290 citations · Full text

Medicine, Pathogenesis, Vascular Malformation +9

Ponatinib (AP24534) inhibits MEKK3-KLF signaling and prevents formation and progression of cerebral cavernous malformations

Jaesung P. Choi, Rui Wang, Xi Yang et al. · Science Advances · 2018 · 52 citations · Full text

Targeting miR-27a/VE-cadherin interactions rescues cerebral cavernous malformations in mice

Jia Li, Yang Zhao, Jaesung P. Choi et al. · PLoS Biology · 2020 · 47 citations · Full text

Molecular Neuroscience, Angiogenesis, Developmental Biology +15

Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican

Courtney C. Hong, Alan T. Tang, Matthew R. Detter et al. · The Journal of Experimental Medicine · 2020 · 46 citations · Full text

Developmental Biology, Angiogenesis, Neuroanatomy +13

Low fluid shear stress conditions contribute to activation of cerebral cavernous malformation signalling pathways

Jia Li, Yang Zhao, Paul Coleman et al. · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · 2019 · 40 citations

Developmental Biology, Neuroanatomy, Cerebrospinal Fluid +5