Alan T. Tang

Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling

Zinan Zhou, Alan T. Tang, Weng-Yew Wong et al. · Nature · 2016 · 321 citations

Medicine, Molecular Medicine, Neuroscience +14

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

Alan T. Tang, Jaesung P. Choi, Jonathan J. Kotzin et al. · Nature · 2017 · 302 citations · Full text

Life Sciences, Microbiology, Neuroscience +13

PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism

Aileen A. Ren, Daniel Snellings, YouRong Sophie Su et al. · Nature · 2021 · 193 citations · Full text

Medicine, Molecular Genetics, Oncology +14

Three‐dimensional Integrated Functional, Structural, and Computational Mapping to Define the Structural “Fingerprints” of Heart‐Specific Atrial Fibrillation Drivers in Human Heart Ex Vivo

Jichao Zhao, Brian J. Hansen, Yufeng Wang et al. · Journal of the American Heart Association · 2017 · 142 citations · Full text

Medicine, Bioengineering, Cardiology +17

Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation

Alan T. Tang, Katie Rose Sullivan, Courtney C. Hong et al. · Science Translational Medicine · 2019 · 73 citations · Full text

Life Sciences, Neuroscience, Pathobiology +17