H. Piechuta

L-663,536 (MK-886) (3-[1-(4-chlorobenzyl)-3-<i>t</i>-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid), a novel, orally active leukotriene biosynthesis inhibitor

John W. Gillard, A W Ford‐Hutchinson, Chi-Chung Chan et al. · Canadian Journal of Physiology and Pharmacology · 1989 · 328 citations

Medicine, Biochemistry, Pharmacology +14

Pharmacology of MK-0591 (3-[1-(4-chlorobenzyl)-3-(<i>t</i>-butylthio)-5-(quinolin-2-yl-methoxy)-indol-2-yl]-2,2-dimethyl propanoic acid), a potent, orally active leukotriene biosynthesis inhibitor

Christine Brideau, Christine Chan, S. Charleson et al. · Canadian Journal of Physiology and Pharmacology · 1992 · 113 citations

Medicine, Pharmacology, Biochemical Pharmacology +12

Discovery of MK-0476, a potent and orally active leukotriene D4 receptor antagonist devoid of peroxisomal enxyme induction

Marc Labelle, Michel Belley, Yves Gareau et al. · Bioorganic & Medicinal Chemistry Letters · 1995 · 100 citations

Medicine, Medicinal Chemistry, Pharmacology +7

Differing mechanisms for leukotriene D4-induced bronchoconstriction in guinea pigs following intravenous and aerosol administration

R. Hamel, P. Masson, A. W. Ford‐Hutchinson et al. · Prostaglandins · 1982 · 70 citations

Veterinary Medicine, Pharmacology, Hypersensitivity +8

L-649,923, Sodium (β<i>S</i>*, γ<i>R</i>*)-4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)-propylthio)-γ-hydroxy-β-methylbenzenebutanoate, a selective, orally active leukotriene receptor antagonist

Thomas R. Jones, Robert N. Young, Éric Champion et al. · Canadian Journal of Physiology and Pharmacology · 1986 · 63 citations

Medicine, Medicinal Chemistry, Pharmacology +9