Christine Hachfeld

Senolytics improve physical function and increase lifespan in old age

Ming Xu, Tamar Pirtskhalava, Joshua N. Farr et al. · Nature Medicine · 2018 · 2.2K citations

Education, Geriatric Medicine, Physiology +14

Targeting cellular senescence prevents age-related bone loss in mice

Joshua N. Farr, Ming Xu, Megan Weivoda et al. · Nature Medicine · 2017 · 1.1K citations · Full text

Medicine, Geriatric Medicine, Aging +9

Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

Allyson K. Palmer, Ming Xu, Yi Zhu et al. · Aging Cell · 2019 · 669 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

Megan Weivoda, Ming Ruan, Christine Hachfeld et al. · Journal of Bone and Mineral Research · 2015 · 158 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +14

Targeted Reduction of Senescent Cell Burden Alleviates Focal Radiotherapy-Related Bone Loss

Abhishek Chandra, Anthony B. Lagnado, Joshua N. Farr et al. · Journal of Bone and Mineral Research · 2020 · 139 citations · Full text

Medicine, Cell Biology, Oncology +17