Anthony B. Lagnado

Senolytics decrease senescent cells in humans: Preliminary report from a clinical trial of Dasatinib plus Quercetin in individuals with diabetic kidney disease

LaTonya J. Hickson, Larissa Prata, Shane A. Bobart et al. · EBioMedicine · 2019 · 1.3K citations · Full text

Veterinary Medicine, Pharmacology, Pharmacotherapy +17

Apoptotic stress causes mtDNA release during senescence and drives the SASP

Stella Victorelli, Hanna Salmonowicz, James Chapman et al. · Nature · 2023 · 600 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Length‐independent telomere damage drives post‐mitotic cardiomyocyte senescence

Rhys Anderson, Anthony B. Lagnado, Damien Maggiorani et al. · The EMBO Journal · 2019 · 511 citations · Full text

Life Sciences, Cell Biology, Genetics +16

Mitochondria-to-nucleus retrograde signaling drives formation of cytoplasmic chromatin and inflammation in senescence

Maria Grazia Vizioli, Tianhui Liu, Karl N. Miller et al. · Genes & Development · 2020 · 335 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Senescent human melanocytes drive skin ageing via paracrine telomere dysfunction

Stella Victorelli, Anthony B. Lagnado, Jessica Halim et al. · The EMBO Journal · 2019 · 244 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12