Laureen Colis

A Targeting Modality for Destruction of RNA Polymerase I that Possesses Anticancer Activity

Karita Peltonen, Laureen Colis, Hester Liu et al. · Cancer Cell · 2014 · 312 citations · Full text

Tumor Biology, Drug Targeting, Engineering +13

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response

Laureen Colis, Karita Peltonen, Paul Sirajuddin et al. · Oncotarget · 2014 · 112 citations · Full text

Identification of Novel p53 Pathway Activating Small-Molecule Compounds Reveals Unexpected Similarities with Known Therapeutic Agents

Karita Peltonen, Laureen Colis, Hester Liu et al. · PLoS ONE · 2010 · 98 citations · Full text

Medicinal Chemistry, Drug Target, Chemoprevention Strategy +15

Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress

Karita Peltonen, Laureen Colis, Hester Liu et al. · Molecular Cancer Therapeutics · 2014 · 89 citations · Full text

Cause Nucleolar Stress, Chemoprevention Strategy, Molecular Biology +18

The cytotoxicity of (−)-lomaiviticin A arises from induction of double-strand breaks in DNA

Laureen Colis, Christina M. Woo, Denise C. Hegan et al. · Nature Chemistry · 2014 · 80 citations · Full text

Genome Instability, Dna Damage, Natural Sciences +9