Paul Sirajuddin

DNA intercalator BMH-21 inhibits RNA polymerase I independent of DNA damage response

Laureen Colis, Karita Peltonen, Paul Sirajuddin et al. · Oncotarget · 2014 · 112 citations · Full text

Small Molecule BMH-Compounds That Inhibit RNA Polymerase I and Cause Nucleolar Stress

Karita Peltonen, Laureen Colis, Hester Liu et al. · Molecular Cancer Therapeutics · 2014 · 89 citations · Full text

Cause Nucleolar Stress, Chemoprevention Strategy, Molecular Biology +18

The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells

Lymor Ringer, Paul Sirajuddin, Lucas Tricoli et al. · Oncotarget · 2014 · 42 citations · Full text

Design, Synthesis, and Structure–Activity Relationships of Pyridoquinazolinecarboxamides as RNA Polymerase I Inhibitors

Laureen Colis, Glen Ernst, Sara Sanders et al. · Journal of Medicinal Chemistry · 2014 · 33 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Chemoprevention Strategy +15

Effective targeting of RNA polymerase I in treatment‐resistant prostate cancer

Jin‐Yih Low, Paul Sirajuddin, Michael S. Moubarek et al. · The Prostate · 2019 · 33 citations