Concepedia

Brian Hurley

BH

3

Publications

226

Citations

3

H-Index

2008

Active since

Affiliations

Novartis (Switzerland)(Current)

Brian Hurley is an author at Novartis (Switzerland) specializing in medicine, natural sciences, and chemical biology.

ORCID

Top concepts

Publications per year

2008–2021

3

Publications

3

Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA)

Atwood K. Cheung, Brian Hurley, Ryan Kerrigan et al. · Journal of Medicinal Chemistry · 2018 · 128 citations · Full text

, , +16

Design and structure–activity relationships of potent and selective inhibitors of undecaprenyl pyrophosphate synthase (UPPS): Tetramic, tetronic acids and dihydropyridin-2-ones

Stefan Peukert, Yingchuan Sun, Rui Zhang et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 83 citations · Full text

, , +9

Use of Intramolecular 1,5-Sulfur–Oxygen and 1,5-Sulfur–Halogen Interactions in the Design of <i>N</i>-Methyl-5-aryl-<i>N</i>-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators

Jake Axford, Moo Je Sung, John I. Manchester et al. · Journal of Medicinal Chemistry · 2021 · 15 citations

Rows per page

1–3 of 3