Jake Axford - Concepedia

Author

Jake Axford

Also Known As

Axford, Jake, Jake Axford

Publications

207

Citations

H-Index

Concepts

All Affiliations

Jake Axford is an author at Novartis (Switzerland) specializing in natural sciences, medicine, and neuromuscular junction.

#	Concept	H-Index	Publications	Citations
1	Medicine	2	2	156
2	Natural Sciences	2	2	156
3	Biochemistry	1	1	28
4	Cell Biology	1	1	128
5	Chemical Biology	1	1	28

Jake Axford

Publications

199

Citations

H-Index

Page 1

	Year	Citations
Discovery of Small Molecule Splicing Modulators of Survival Motor Neuron-2 (SMN2) for the Treatment of Spinal Muscular Atrophy (SMA) Atwood K. Cheung, Brian Hurley, Ryan Kerrigan, Journal of Medicinal Chemistry GeneticsMolecular BiologyCytoskeletonSplicing VariantSmn2 Pre-mrna	2018	128
Discovery of a novel chemotype of potent human ENaC blockers using a bioisostere approach. Part 1: Quaternary amines Thomas A. Hunt, Hazel C. Atherton-Watson, Jake Axford, Bioorganic & Medicinal Chemistry Letters Combinatorial ChemistryQuaternary AminesMedicinal ChemistryBioorganic ChemistryNovel Chemotype	2011	28
Discovery of Ligands for TRIM58, a Novel Tissue-Selective E3 Ligase Klemens Hoegenauer, Shaojian An, Jake Axford, ACS Medicinal Chemistry Letters	2023	28
Use of Intramolecular 1,5-Sulfur–Oxygen and 1,5-Sulfur–Halogen Interactions in the Design of <i>N</i>-Methyl-5-aryl-<i>N</i>-(2,2,6,6-tetramethylpiperidin-4-yl)-1,3,4-thiadiazol-2-amine SMN2 Splicing Modulators Jake Axford, Moo Je Sung, John I. Manchester, Journal of Medicinal Chemistry	2021	15

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