Concepedia

Author

Philipp Heine

University of ZurichORCID

Also Known As

P. Heine, Philipp Heine

11

Publications

670

Citations

7

H-Index

23

Concepts

All Affiliations

University of Zurich
PH

About

Philipp Heine is an author at University of Zurich specializing in molecular biology, biochemistry, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Natural Sciences

4

4

422

2

Biochemistry

4

4

422

3

Medicine

3

3

121

4

Biomolecular Engineering

2

2

52

5

Chemical Biology

2

2

59

Philipp Heine

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7

Publications

668

Citations

7

H-Index

YearCitations

PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

Hsin‐Yung Yen, Kin Kuan Hoi, Idlir Liko,

Nature

2018

301

Structure of signaling-competent neurotensin receptor 1 obtained by directed evolution in<i>Escherichia coli</i>

Pascal Egloff, Matthias Hillenbrand, Christoph Klenk,

Proceedings of the National Academy of Sciences

2014

207

Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism

Mattia Deluigi, A. Klipp, Christoph Klenk,

Science Advances

2021

62

SPR-based fragment screening with neurotensin receptor 1 generates novel small molecule ligands

Sylwia Huber, Fabio Casagrande, Melanie N. Hug,

PLoS ONE

2017

32

Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries

Anirudh Ranganathan, Philipp Heine, Axel Rudling,

ACS Chemical Biology

2016

27

A cleavable ligand column for the rapid isolation of large quantities of homogeneous and functional neurotensin receptor 1 variants from E. coli

Pascal Egloff, Mattia Deluigi, Philipp Heine,

Protein Expression and Purification

2014

20

High-Throughput Fluorescence Polarization Assay to Identify Ligands Using Purified G Protein-Coupled Receptor

Philipp Heine, Gesa Witt, A. Gilardi,

SLAS DISCOVERY

2019

19

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