Sialylation and fucosylation of epidermal growth factor receptor suppress its dimerization and activation in lung cancer cells

Ying-Chih Liu, Hsin‐Yung Yen, Chien‐Yu Chen, +9

Proceedings of the National Academy of Sciences

Cancer ResearchProtein GlycosylationAbnormal GlycosylationMedicineNatural Sciences +13

PtdIns(4,5)P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling

Hsin‐Yung Yen, Kin Kuan Hoi, Idlir Liko, +12

Nature

Protein ChemistryProtein FunctionSignal TransductionActive StatesBiochemistry +5

Structural insights into the lipid and ligand regulation of serotonin receptors

Peiyu Xu, Sijie Huang, Huibing Zhang, +16

Nature

Signal TransductionBiochemistryG Protein-coupled ReceptorMedicineNeurotransmitter +7

An electron transfer path connects subunits of a mycobacterial respiratory supercomplex

Hongri Gong, Jun Li, Ao Xu, +23

Science

Combining native and ‘omics’ mass spectrometry to identify endogenous ligands bound to membrane proteins

Joseph Gault, Idlir Liko, Michael Landreh, +16

Nature Methods

Proteomic TechnologyBiochemistryNatural SciencesMedicineOmics Technology +10

Effect of sialylation on EGFR phosphorylation and resistance to tyrosine kinase inhibition

Hsin‐Yung Yen, Ying-Chih Liu, Nai-Yu Chen, +6

Proceedings of the National Academy of Sciences

State-dependent Lipid Interactions with the A2a Receptor Revealed by MD Simulations Using In Vivo-Mimetic Membranes

Wanling Song, Hsin‐Yung Yen, Carol V. Robinson, +1

Structure

Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors

Leonhard H. Urner, Idlir Liko, Hsin‐Yung Yen, +10

Nature Communications

Differential Receptor Binding Affinities of Influenza Hemagglutinins on Glycan Arrays

Hsin-Yu Liao, Che‐Hsiung Hsu, Shih-Chi Wang, +10

Journal of the American Chemical Society

Microbial PathogensGlycobiologyImmunologyImmunodominanceFlu Vaccination +14

Cell-permeable probe for identification and imaging of sialidases

Charng‐Sheng Tsai, Hsin‐Yung Yen, Meng‐I Lin, +7

Proceedings of the National Academy of Sciences