Sijie Huang

Structures of the Omicron spike trimer with ACE2 and an anti-Omicron antibody

Wanchao Yin, Youwei Xu, Peiyu Xu et al. · Science · 2022 · 299 citations · Full text

Virus Structure, Viral Evolution, Omicron Spike Trimer +10

Structural insights into the lipid and ligand regulation of serotonin receptors

Peiyu Xu, Sijie Huang, Huibing Zhang et al. · Nature · 2021 · 264 citations

Signal Transduction, Biochemistry, G Protein-coupled Receptor +9

Structural insights into the human D1 and D2 dopamine receptor signaling complexes

Youwen Zhuang, Peiyu Xu, Chunyou Mao et al. · Cell · 2021 · 251 citations · Full text

Molecular Pharmacology, Human D1, Functional Selectivity +10

Cryo-EM structure of an activated VIP1 receptor-G protein complex revealed by a NanoBiT tethering strategy

Jia Duan, Dandan Shen, X. Edward Zhou et al. · Nature Communications · 2020 · 218 citations · Full text

GPCRs steer Gi and Gs selectivity via TM5-TM6 switches as revealed by structures of serotonin receptors

Sijie Huang, Peiyu Xu, Dandan Shen et al. · Molecular Cell · 2022 · 145 citations · Full text

Signal Transduction, G Protein-coupled Receptor, Medicine +10