Anirudh Ranganathan

Insights into the Role of Asp79^2.50in β₂Adrenergic Receptor Activation from Molecular Dynamics Simulations

Anirudh Ranganathan, Ron O. Dror, Jens Carlsson · Biochemistry · 2014 · 80 citations

Mapping the Interface of a GPCR Dimer: A Structural Model of the A2A Adenosine and D2 Dopamine Receptor Heteromer

Dasiel O. Borroto‐Escuela, David Rodríguez, Wilber Romero‐Fernandez et al. · Frontiers in Pharmacology · 2018 · 71 citations · Full text

Complementarity between in Silico and Biophysical Screening Approaches in Fragment-Based Lead Discovery against the A_2AAdenosine Receptor

Dan Chen, Anirudh Ranganathan, Adriaan P. IJzerman et al. · Journal of Chemical Information and Modeling · 2013 · 64 citations

Drug Target, Hit Identification, Fragment-based Lead Discovery +17

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site

Pierre Matricon, Anirudh Ranganathan, Eugene Warnick et al. · Scientific Reports · 2017 · 64 citations · Full text

Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries

Anirudh Ranganathan, Philipp Heine, Axel Rudling et al. · ACS Chemical Biology · 2016 · 27 citations · Full text

Crystal Structure, Peptide Engineering, Molecular Biology +21