Pierre Matricon

GPCRmd uncovers the dynamics of the 3D-GPCRome

Ismael Rodríguez‐Espigares, Mariona Torrens‐Fontanals, Johanna K. S. Tiemann et al. · Nature Methods · 2020 · 186 citations · Full text

Geometric Modeling, Engineering, Natural Sciences +8

Energy Landscapes Reveal Agonist Control of G Protein-Coupled Receptor Activation via Microswitches

Oliver Fleetwood, Pierre Matricon, Jens Carlsson et al. · Biochemistry · 2020 · 76 citations · Full text

Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling

Julian Petersen, Shane C. Wright, David Rodríguez et al. · Nature Communications · 2017 · 73 citations · Full text

Fragment optimization for GPCRs by molecular dynamics free energy calculations: Probing druggable subpockets of the A 2A adenosine receptor binding site

Pierre Matricon, Anirudh Ranganathan, Eugene Warnick et al. · Scientific Reports · 2017 · 64 citations · Full text

Ligand design by targeting a binding site water

Pierre Matricon, R. Rama Suresh, Zhan‐Guo Gao et al. · Chemical Science · 2020 · 61 citations · Full text