Ritesh Tichkule

Human HDAC isoform selectivity achieved via exploitation of the acetate release channel with structurally unique small molecule inhibitors

Lewis Whitehead, Markus Dobler, Branko Radetich et al. · Bioorganic & Medicinal Chemistry · 2011 · 153 citations · Full text

Biochemistry, Natural Sciences, Medicine +7

6-Amino-3-methylpyrimidinones as Potent, Selective, and Orally Efficacious SHP2 Inhibitors

Patrick Sarver, Michael Acker, Jeffrey T. Bagdanoff et al. · Journal of Medicinal Chemistry · 2019 · 85 citations · Full text

Medicinal Chemistry, Allosteric Shp2 Inhibitors, Drug Target +15

In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569

Thomas F. Gamage, Bogna M. Ignatowska‐Jankowska, Jenny L. Wiley et al. · Behavioural Pharmacology · 2014 · 64 citations · Full text

Cannabis Use, Molecular Pharmacology, Allergy +15

Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors

Jakub Fichna, Misha Bawa, Ganesh A. Thakur et al. · PLoS ONE · 2014 · 64 citations · Full text

Novel Electrophilic and Photoaffinity Covalent Probes for Mapping the Cannabinoid 1 Receptor Allosteric Site(s)

Pushkar M. Kulkarni, Abhijit Kulkarni, Anisha Korde et al. · Journal of Medicinal Chemistry · 2015 · 60 citations · Full text

Molecular Biology, Chemical Biology, Optogenetics +18