Carrie Whitney‐Pickett

Development of a new permeability assay using low‐efflux MDCKII cells

Li Di, Carrie Whitney‐Pickett, John P. Umland et al. · Journal of Pharmaceutical Sciences · 2011 · 311 citations

Membrane Transport, Membrane Biology, Biomedical Engineering +6

pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery

Manthena V. S. Varma, Iain Gardner, Stefanus J. Steyn et al. · Molecular Pharmaceutics · 2012 · 163 citations

Pharmaceutical Science, Permeability Criteria, Physiologically-based Pharmacokinetic Modeling +27

The JAK-3 inhibitor CP-690550 is a potent anti-inflammatory agent in a murine model of pulmonary eosinophilia

Elizabeth M. Kudlacz, Maryrose J. Conklyn, Catharine J. Andresen et al. · European Journal of Pharmacology · 2008 · 95 citations

Inflammation, Jak-3 Inhibitor Cp-690550, Pulmonary Eosinophilia +14

Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535

Allen J. Duplantier, Mark A. Dombroski, Chakrapani Subramanyam et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 75 citations · Full text

Medicinal Chemistry, Clinical Candidate Ce-224,535, Biochemistry +9

Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X7 receptor

Chakrapani Subramanyam, Allen J. Duplantier, Mark A. Dombroski et al. · Bioorganic & Medicinal Chemistry Letters · 2011 · 20 citations · Full text

Medicinal Chemistry, Drug Target, Biochemistry +10