Iain Gardner - Concepedia

Author

Iain Gardner

Simcyp (United Kingdom)ORCID

Also Known As

Gardner, Iain, IAIN GARDNER, Iain B Gardner, Iain B. Gardner, Iain Gardner

142

Publications

Citations

H-Index

Concepts

All Affiliations

Simcyp (United Kingdom)Pfizer (United Kingdom)Pfizer (United States)University of Konstanz Centre for Human Drug Research

About

Iain Gardner is an author at Simcyp (United Kingdom) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	18	23	1.2K
2	Natural Sciences	3	3	192
3	Allergy	3	3	117
4	Engineering	2	2	217
5	Public Health	2	2	57

Iain Gardner

Publications

2.6K

Citations

H-Index

Page 1

	Year	Citations
Modelling and PBPK Simulation in Drug Discovery Hannah M. Jones, Iain Gardner, Kenny J. Watson The AAPS Journal EngineeringPharmacokinetic ModelingMedicineComputational BiologyRational Drug Design	2009	198
Zebrafish based assays for the assessment of cardiac, visual and gut function — potential safety screens for early drug discovery Stéphane Berghmans, Paul Butler, Paul Goldsmith, Journal of Pharmacological and Toxicological Methods Animal TestingPreclinical Drug EvaluationMedicinePhysiologyBioanalysis	2008	187
pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery Manthena V. S. Varma, Iain Gardner, Stefanus J. Steyn, Molecular Pharmaceutics Pharmaceutical SciencePermeability CriteriaPhysiologically-based Pharmacokinetic ModelingPharmacodynamic ModelingMedicinal Chemistry	2012	163
A Comparison of the Covalent Binding of Clozapine and Olanzapine to Human Neutrophils In Vitro and In Vivo Iain Gardner, J. Steven Leeder, Nasir Zahid, Molecular Pharmacology	1998	118
Simulation of Human Intravenous and Oral Pharmacokinetics of 21 Diverse Compounds Using Physiologically Based Pharmacokinetic Modelling Hannah M. Jones, Iain Gardner, Wendy T. Collard, Clinical Pharmacokinetics Physiologically Based PharmacokineticsPharmacokinetic ModellingPharmacodynamicsPharmacological StudyPhysiology	2011	111
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations Wiebke Albrecht, Franziska Kappenberg, Tim Brecklinghaus, Archives of Toxicology	2019	104
A Bottom-Up Whole-Body Physiologically Based Pharmacokinetic Model to Mechanistically Predict Tissue Distribution and the Rate of Subcutaneous Absorption of Therapeutic Proteins Katherine L. Gill, Iain Gardner, Linzhong Li, The AAPS Journal	2015	102
A Comparison of the Oxidation of Clozapine and Olanzapine to Reactive Metabolites and the Toxicity of these Metabolites to Human Leukocytes Iain Gardner, Nasir Zahid, Duncan J. MacCrimmon, Molecular Pharmacology	1998	95
Application of PBPK modelling in drug discovery and development at Pfizer Hannah M. Jones, Maurice Dickins, Kuresh Youdim, Xenobiotica	2011	93
The Metabolism and Toxicity of Furosemide in the Wistar Rat and CD-1 Mouse: a Chemical and Biochemical Definition of the Toxicophore Dominic P. Williams, Daniel J. Antoine, Philip Butler, Journal of Pharmacology and Experimental Therapeutics	2007	71

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