Brian C. Vanderplas

Commercial Route Research and Development for SGLT2 Inhibitor Candidate Ertugliflozin

Paul Bowles, Steven J. Brenek, Stéphane Caron et al. · Organic Process Research & Development · 2013 · 66 citations

Combinatorial Chemistry, Bioorganic Chemistry, Organic Chemistry +19

Safe Execution of a Large-Scale Ozonolysis:  Preparation of the Bisulfite Adduct of 2-Hydroxyindan-2-carboxaldehyde and Its Utility in a Reductive Amination

John A. Ragan, David J. am Ende, Steven J. Brenek et al. · Organic Process Research & Development · 2003 · 54 citations

Engineering, Safe Execution, Organic Chemistry +16

A Chemoenzymatic Route to Chiral Intermediates Used in the Multikilogram Synthesis of a Gamma Secretase Inhibitor

Michael P. Burns, Carlos A. Martinez, Brian C. Vanderplas et al. · Organic Process Research & Development · 2017 · 39 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Chiral Intermediates +15

The preparation of β-substituted amines from mixtures of epoxide opening products via a common aziridinium ion intermediate

Shelby R. Anderson, Joshua T. Ayers, Keith M. DeVries et al. · Tetrahedron Asymmetry · 1999 · 28 citations

Enantioselective Synthesis, Engineering, Organic Chemistry +5

Development of two synthetic routes to CE-178,253, a CB1 antagonist for the treatment of obesity

Thomas A. Brandt, Stéphane Caron, David B. Damon et al. · Tetrahedron · 2008 · 24 citations

Metabolic Syndrome, Biochemistry, Functional Selectivity +8