Stéphane Caron

New ligands for nickel catalysis from diverse pharmaceutical heterocycle libraries

Eric C. Hansen, Dylan Pedro, Alexander C. Wotal et al. · Nature Chemistry · 2016 · 206 citations · Full text

Medicinal Chemistry, Engineering, Natural Sciences +8

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development

Krista L. Dobo, Nigel Greene, Michelle O. Cyr et al. · Regulatory Toxicology and Pharmacology · 2006 · 127 citations

Structure-based Assessment, Medicinal Chemistry, Drug Purity +16

Directed Ortho Metalation of Neopentyl Benzoates with LDA:  Preparation of Arylboronic Acids

Stéphane Caron, Joel M. Hawkins · The Journal of Organic Chemistry · 1998 · 96 citations

Arylboronic Acids, Neopentyl Benzoates, Chemical Engineering +14

Preparation of Tertiary Benzylic Nitriles from Aryl Fluorides

Stéphane Caron, Enrique Vázquez, Jill M. Wojcik · Journal of the American Chemical Society · 2000 · 95 citations

Combinatorial Chemistry, Aryl Fluoridesstéphane Caron, Molecular Sciences +7

Process Research and Development of an NK-1 Receptor Antagonist. Enantioselective Trifluoromethyl Addition to a Ketone in the Preparation of a Chiral Isochroman

Stéphane Caron, Nga M., Janice E. Sieser et al. · Organic Process Research & Development · 2007 · 93 citations

Nk-1 Receptor Antagonist, Natural Product Synthesis, Engineering +13