Nigel Greene

Physiochemical drug properties associated with in vivo toxicological outcomes

Jason D. Hughes, Julian Blagg, David A. Price et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 945 citations

Preclinical Drug Evaluation, Medicine, Toxicology +5

Knowledge-Based Expert Systems for Toxicity and Metabolism Prediction: DEREK, StAR and METEOR

Nigel Greene, Philip N. Judson, J. J. Langowski et al. · SAR and QSAR in environmental research · 1999 · 254 citations

Engineering, Lhasa Limited, Computational Medicine +24

Developing Structure−Activity Relationships for the Prediction of Hepatotoxicity

Nigel Greene, Lilia Fisk, Russell Naven et al. · Chemical Research in Toxicology · 2010 · 161 citations

Marketed Drugs, Knowledge Base, Medicinal Chemistry +15

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic<i>in vitro</i>Assays

Falgun Shah, Louis Leung, Hugh A. Barton et al. · Toxicological Sciences · 2015 · 139 citations · Full text

Plasma Cmax, Pharmacotherapy, Human Plasma Cmax +23

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development

Krista L. Dobo, Nigel Greene, Michelle O. Cyr et al. · Regulatory Toxicology and Pharmacology · 2006 · 127 citations

Structure-based Assessment, Medicinal Chemistry, Drug Purity +16