Krista L. Dobo

In silico toxicology protocols

Glenn J. Myatt, Ernst Ahlberg, Yumi Akahori et al. · Regulatory Toxicology and Pharmacology · 2018 · 234 citations · Full text

Toxicology Testing, Environmental Health, Toxicology +18

The application of structure-based assessment to support safety and chemistry diligence to manage genotoxic impurities in active pharmaceutical ingredients during drug development

Krista L. Dobo, Nigel Greene, Michelle O. Cyr et al. · Regulatory Toxicology and Pharmacology · 2006 · 127 citations

Structure-based Assessment, Medicinal Chemistry, Drug Purity +16

Use of in silico systems and expert knowledge for structure-based assessment of potentially mutagenic impurities

Andreas Sutter, Alexander Amberg, Scott Boyer et al. · Regulatory Toxicology and Pharmacology · 2013 · 123 citations

Expert Knowledge, Chemical Safety, Engineering +15

Principles and procedures for implementation of ICH M7 recommended (Q)SAR analyses

Alexander Amberg, Lisa Beilke, Joel P. Bercu et al. · Regulatory Toxicology and Pharmacology · 2016 · 108 citations · Full text

Engineering, Pathology, Impurity Qualification +22

In silico methods combined with expert knowledge rule out mutagenic potential of pharmaceutical impurities: An industry survey

Krista L. Dobo, Nigel Greene, Charlotta Fred et al. · Regulatory Toxicology and Pharmacology · 2012 · 84 citations

Chemical Engineering, Residue (Chemistry), Engineering +15