Olivier Dirat

Callipeltoside A: Total Synthesis, Assignment of the Absolute and Relative Configuration, and Evaluation of Synthetic Analogues

Barry M. Trost, Janet L. Gunzner, Olivier Dirat et al. · Journal of the American Chemical Society · 2002 · 197 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Potential for the Formation of <i>N</i>-Nitrosamines during the Manufacture of Active Pharmaceutical Ingredients: An Assessment of the Risk Posed by Trace Nitrite in Water

Ian W. Ashworth, Olivier Dirat, Andrew Teasdale et al. · Organic Process Research & Development · 2020 · 124 citations

Pharmacy, Toxicology, Analytical Toxicology +9

Practical and Science-Based Strategy for Establishing Acceptable Intakes for Drug Product <i>N</i>-Nitrosamine Impurities

Krista L. Dobo, Michelle Kenyon, Olivier Dirat et al. · Chemical Research in Toxicology · 2022 · 86 citations · Full text

Pharmacy, Pharmacology, Toxicology +14

Callipeltoside A: Assignment of Absolute and Relative Configuration by Total Synthesis We thank the National Science Foundation and the National Institutes of Health for their generous support of our programs. OD was supported in part by a fellowship from the Association pour la Recherche contre le Cancer (ARC). J.L.G. was supported in part by a NIH postdoctoral fellowship from the National Cancer Institute. Mass spectra were provided by the Mass Spectroscopy Facility at the University of California, San Francisco supported by the NIH Division of Research Resources, and the Mass Spectrometry Facility at University of California, Irvine. We thank Dr. John Greaves of the latter facility for his assistance.

Barry M. Trost, Olivier Dirat, Janet L. Gunzner · Angewandte Chemie International Edition · 2002 · 72 citations

Natural Sciences, Chemistry, Medicinal Chemistry +9

Approaches and Considerations for the Investigation and Synthesis of <i>N</i>-Nitrosamine Drug Substance-Related Impurities (NDSRIs)

Ian W. Ashworth, Alexander Blanazs, Jonathan J. Byrne et al. · Organic Process Research & Development · 2023 · 35 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +12