Alison E. McGonagle

First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to Olaparib

Dominic I. James, Kate M. Smith, Allan M. Jordan et al. · ACS Chemical Biology · 2016 · 148 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

Catalytic aza-Wittig Cyclizations for Heteroaromatic Synthesis

Stephen P. Marsden, Alison E. McGonagle, Ben McKeever‐Abbas · Organic Letters · 2008 · 142 citations

Natural Sciences, Chemistry, Catalysis +12

Toxoflavins and Deazaflavins as the First Reported Selective Small Molecule Inhibitors of Tyrosyl-DNA Phosphodiesterase II

Ali Raoof, Paul Depledge, Niall M. Hamilton et al. · Journal of Medicinal Chemistry · 2013 · 61 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +15

Development of (4-Cyanophenyl)glycine Derivatives as Reversible Inhibitors of Lysine Specific Demethylase 1

Daniel P. Mould, Cristina Alli, Ulf Bremberg et al. · Journal of Medicinal Chemistry · 2017 · 48 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Cell-Active Small Molecule Inhibitors of the DNA-Damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG): Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

Bohdan Waszkowycz, Kate M. Smith, Alison E. McGonagle et al. · Journal of Medicinal Chemistry · 2018 · 32 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14